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KMID : 0386520120200020079
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Research Institute of Korean Medicone
2012 Volume.20 No. 2 p.79 ~ p.89
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Effects of Vanadium Water on Cancer-related Fatigue of Non Advanced Thyroid Cancer Patients: Randomized, Three armed, Triple Blinded Controlled Trial
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Zheng Hong-mei
Kim Dong-Hee
Lee Suk-Hoon
Kim Kyung-Soon
Yoo Hwa-Seung
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Abstract
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Objective: This study was conducted to evaluate of efficacy and safety of Vanadium Water (VW) on Cancer related Fatigue of Non-advanced Cancer Patients.
Methods: Experimental Group Administration. Participants in treatment group consumed three 500 ml/bottle bottles of Jeju Island’s VW, which contains 40.2 of vanadium, three times a day (morning, afternoon, evening) for 4 weeks (28 days) without any additional treatments for fatigue improvement. The control group participants consumed three 500 ml/bottle bottles of ordinary water (0 of vanadium) three times a day for the same period of time without any additional treatments for fatigue improvement.
Results: After 4 weeks of VW consumption, total score of Revised Piper Fatigue Scale (RPFS) was reduced 30% and basal score after Fisher’s Exact Test resulted statistical borderline significance (p=0.0799) and result of t-test of comparison between two groups’ RPFS total score and fatigue cognitive/mood changes resulted statistical significance (p=0.0112). In detail, only 36.4% of control group (N=11) showed improvement while 77.8% of treatment group (N=9) showed fatigue improvement and thyroid hormone level changes. No other lab measures indicated any significant differences between two groups.
Conclusion: Daily consumption of 1.5 L of Vanadium water for 4 weeks showed improvement of non-advanced cancer patients’ fatigue.
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KEYWORD
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Chronic fatigue, Vanadium Water, Thyroid cancer, Revised Piper Fatigue Scale, Randomized Controlled Trial
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